BIO and CHM 4104: Biochemistry

 

I.                   General information:

a.       Program affiliation: Biology & Chemistry

b.      Course number and title:  BIO 4104 & CHM 4104: Biochemistry

c.       Meeting times: TR 8:00-10:45

d.      Rooms: S-127 & S-112

e.       Prerequisites:   CHM 3014; Recommended Bio 3024

f.        Professor: Dr. Sean T. Coleman Office: S-222  Phone: 979-1364  Email: scolema@ozarks.edu

g.       Office Hrs: MWF: 10:00-11:00 MTWF: 1:00-2:00

h.       Last day to drop: November 4th 

i.         Course web-site:  http://ozarks.ucompass.com and http://departments.ozarks.edu/msc/Biology/courses.htm

 

II.                Textbook and Lab Manual:

a.       Campbell, MK and Farrell, SO 2003.  Biochemistry. 4th ed. Harcourt Brace and Company, San Orlando, Fl.

b.      Laboratory Notebook.

 

III.             Catalog Description:  Introduction to the major classes of biological molecules and their chemistry in living systems.

 

IV.              Intended Student Outcomes: 

 

1.      Students will communicate effectively

b.      use effective strategies to organize thoughts, develop a message and document sources for article reviews and the discussion web

c.       learn to present a message skillfully when reviewing Biochemistry articles

d.      clearly and effectively express ideas and actively listen to the ideas of others during discussions

 

2.      Students will think critically

a.       read Biochemistry articles and text with comprehension

d.      evaluate and analyze arguments from more than one perspective in order to prepare for debates and discussions

e.       recognize and form interpretations, generalizations, or causal explanations appropriate to the study of Biochemistry

 

3.      Students will have knowledge of human culture

a.       identify, describe and use the salient methods, skills or ways of knowing in the fine arts, humanities, social sciences, mathematics and natural sciences

                                                                                                   i.      Specifically Biochemical principles and applications

e.       Use available technologies to gather and process Biochemical information effectively

 

4.      Students will be aware of their responsibilities to themselves, to humanity, to their planet and to their creator

e.       examine personal lifestyle, ethics, integrity, values and priorities

f.        respect individuals with beliefs, backgrounds or abilities different from their own

g.       contribute to the welfare of their community and ecosystem

 

V.                 Attendance:  You will be expected to attend every lecture.  Exam questions are taken primarily from the material covered in lecture.  In addition you will be expected to be prepared for and participate in discussions.  Attendance and participation will be the determining factors for assigning the final grade to a student whose total points fall near a borderline.  All students are required to participate in the laboratory portion of the course.  You are expected to attend on time and participate in the entire lab.  Three unexcused absences in the lab will result in a failing grade for the entire course.  Excused absences will require either prior approval or written verification.  Three absences for ANY reason will result in an incomplete for the course. 

 

Make-up lecture exams are given at the discretion of the professor.  In case of illness, emergency or other excusable absence contact the professor as soon as possible.  Please leave a message on the answering machine at the phone number listed above.  Written verification will be required to take the make-up exam.  If you know you will miss the exam before hand please contact the professor, as make-up exams are generally more difficult than the regular exam.

 

The student is responsible for all assignments, late assignments will be docked a minimum of 10% per day late.  The student must complete all assignments.  If an assignment is not turned in by the final day of class the professor can dock the student’s overall grade one full grade for each missed assignment or exam.  This is on top of the zero points received for that assignment.

 

VI.              Academic Honesty:  Cheating will not be tolerated!  The minimum penalty for cheating will be a zero (0) for that assignment, exam or quiz.  Other penalties can include but are not limited to failing the course, academic probation and/or suspension from the University.  Plagiarism is also a form of cheating and will be dealt with accordingly.  Verbatim use of words from sources without proper notation will result in a minimum of a single grade deduction and/or see above.  Furthermore, when working in groups each person must complete and hand in their own work in their own words.  Finally, assignments completed for this class must not be used in another class without the consent of both professors.

 

VII.           Evaluation:  Assignments, Exams, Labs and Quizzes.

a.       Written assignments:  Any written assignment must be typed, double-spaced and are to be turned in immediately following the class period on the date they are due.  Late assignments will be penalized 10% per class day they are late.  Any assignment turned in more than two weeks late will receive a zero (0).

b.      Labs:  Points will be awarded in lab for keeping a laboratory notebook in a clear and concise manner with good descriptions hypotheses, what was done, observations, results and discussion (at least 10 pts. per lab).  Exams will also test some of the knowledge gained in lab.

                                                               i.      Journal Style Research Paper:  An independent research project will be done in conjunction with the enzyme kinetics lab. Students will design and carryout research projects on the effects of different conditions on enzyme kinetics.  Students will then write up their findings as if they were to be published in a scientific journal.  These findings will be presented to their peers in a formal presentation of 10-15 minutes.  This assignment is worth 100 points and will be based on lab, writing, discussion and presentation performance.

                                                             ii.      Lab Points:  At least 50 points (approximately one-half of an exam grade) is available to students based on their attendance, participation and preparedness for lab.  All students will start with zero points and will be awarded points based on performance in the lab setting.

c.       Quizzes:  Quizzes:  A quiz will be given at the start of nearly every new chapter (~ 10 points).  This will require the student to have, at the minimum, read the chapter before coming to class.  The student may use notes they have taken on the chapter for these chapter quizes. Unscheduled quizzes (10 points maximum) may be given randomly throughout the semester due to lack of preparedness or participation by the students.

d.      Web-based bulletin board discussions:  Students will be expected to participate in discussions related to science on the web, this will be for your participation grade as well as up to the equivalent of one exam grade.

e.       Pre-unit quiz:  A quiz will be administered before the beginning of each unit over the assigned reading for that unit.  The quizzes will be worth no less than 10 points each.

f.        Lecture exams:  There will be four exams given on the days indicated.  They will be composed of mostly short and long answer essay questions.  However, multiple choice, fill in the blank, matching and label the figure questions could also make an appearance.  The majority of the exam will come from lectures, some questions based on lab material (10-20%) will also make up a portion of the exam.  Exams will be 100 points except for the final, which will be worth 100-200 points.  The final will be mostly from the last unit (approximately 75%/25%) with a few cumulative questions.

g.       Extra credit:  Will not be given unless it is announced in class and everyone has an opportunity to receive it.

VIII.        Final grades:  The final grades will be based on a scale of the total points earned in the class.  The most stringent scale will be 90-100% an A, 80-89% a B, 70-79% a C, 60-69% a D and 59% and less an F.  Any grade near the borderline may be raised at the professor’s discretion (please see article V. Attendance).  Letter grades announced for individual exams are purely estimates of your general ranking for that exam.  Only your final numerical average will be considered in assigning your final grade.

 

IX.              ADA Statement:  If any member of the class has a documented disability and needs special accommodations, the instructor will work with the student and the office of Student Support Services or the Jones Learning Center to provide reasonable accommodation to ensure the student a fair opportunity to perform in this class.  In order to plan for optimum success, please advise the instructor of the disability and the desired accommodations as soon as possible.  Students are strongly encouraged to notify the instructor during the first week of classes.  Without ample planning / preparation time, we cannot assure the availability of needed accommodations in a timely manner.

 

X.                 This Syllabus is Subject to Change at the Discretion of the Professor.

 

XI.              Most Importantly Ask Questions:  If you have any questions about this syllabus, the material, exams or assignments ask the professor.

 

XII.           Dates and Assignments.

 

Week

Discussion

Lab

 Aug 26th                   T.  

R.

Syllabus/ Ch. 1: Intro

Ch. 2: Water

 

Lecture

Sept 2nd                      T.  

R.

Ch. 3: Amino Acids

 

 

PAGE

Sept 9th                  T.

R.

Ch. 4: Proteins

 

 

Affinity Chrom.

Sept 16th              T.

R.

Assessment Day

 

 

Exam I

Sept 23rd                   T.

R.

Ch. 5: Enzymes

 

 

Affinity Chrom.

Sept 30th                   T.

R.

Ch. 6: Protein Behavior

 

 

Enzyme Kinetics

Oct 7th                 T.

R.

Ch. 7: Lipids

 

 

Enzyme Kinetics

Oct 14th                     T.

R.

Ch. 8: Nucleic Acids

 

 

Enzyme Kinetics

Oct 21st                      T.

R.

Exam II

No Class

 

No Lab

Oct 28th                     T.

R.

Ch. 9 and 10: Nucleic Acid Biosynthesis

 

 

Western Blotting

Nov 4th                      T.

R.

Ch. 11: Translation

 

 

Western Blotting

Nov 11th                    T.

R.

Ch. 12: Energy Change

 

 

Cloning a PCR Prod.

Nov 18th                    T.

R.

Exam III

 

 

Cloning a PCR Prod.

Nov 25th                   T.

R.

Ch. 13: Carbohydrates

No Class

 

No Lab

Dec 2nd                       T.

R.

Ch. 14 and 16: Glycolysis and Krebs Cycle

 

Cloning a PCR Prod.

Dec 9th                        T.

R.

Ch. 17: ETC and Oxidative Phosph.

 

Open/Review

Dec 16th                     T.

 

Final Exam

Tuesday December 16th, 8:00 to 10:30